Dinh-Quy Nguyen

SirtSAGE: A Structural-Gated Graph Attention Framework for the Unified Classification and Evolutionary Mapping of Sirtuin Proteins

This work introduces SirtSAGE (Sirtuin Structural-Aware Graph-Evolutionary framework), a hybrid architecture designed to distill evolutionary embeddings through physical structural constraints that outperforms state-of-the-art 1D-CNN baselines in predictive robustness, despite operating under a substantially more strin...