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Cellular Senescence in Osteoarthritis: Mechanisms, Pathological Roles, and Therapeutic Opportunities
Osteoarthritis (OA) is a prevalent whole‐joint disorder characterized by progressive alterations in articular cartilage, synovium, subchondral bone, and surrounding tissues. Increasing evidence implicates cellular senescence as a potential contributor to OA‐associated tissue dysfunction, although the extent and directi...