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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Dirk Mijnlieff

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Review Open access Aug 2026

Bracing for the storm: emerging resistance mechanisms to KRAS inhibitors in pancreatic cancer and strategies to overcome them

Current knowledge on molecular resistance to RAS-directed inhibitors in PDAC is summarized, organized into five categories: intrinsic resistance, KRAS-dependent mechanisms, KRAS-independent bypass signaling, downstream pathway reactivation, and tumor microenvironment (TME)-mediated resistance.

M. Pagano Mariano, Enrica Sgarilli, Dirk Mijnlieff et al. · 0 citations

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