Breast Cancer (BC) continues to be a predominant cause of cancer-related death globally, with clinical therapy impeded by off-target toxicity and limited therapeutic windows of traditional chemotherapeutics, especially across various molecular subtypes. This study critically assesses the integration of advanced nanocar...
Usamah Sayed, Diyora Azamova, A. Abdulqader et al.· International journal of pha...· 0 citations
The transcriptional coactivators p300 and CREB-binding protein (CBP) integrate chromatin remodeling, enhancer activity, lysine acetylation, immune signaling, and tumor-suppressor control, making them recurrent targets of viral proteins. This narrative review examines p300/CBP at the virus-cancer interface, prioritizing...
A. Atoom, J. Rizaev, D. Polatova et al.· Cancer Treatment and Researc...· 0 citations
Breast cancer remains a significant clinical challenge, particularly in triple‑negative breast cancer (TNBC), in which therapeutic resistance limits treatment efficacy. Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has emerged as a promising strategy to overcome resistance in...
S. Mohammad, A. Vasudevan, Samreet Raizal Rodrigues et al.· Asia-Pacific Journal of Clin...· 0 citations
Oncolytic virotherapy has evolved from a tumor-selective cytolytic strategy into a programmable immunotherapeutic platform that reshapes the tumor microenvironment (TME). Oncolytic viruses (OVs) selectively infect malignant cells, induce immunogenic cell death, release tumor antigens, and activate innate and adaptive i...
A. Atoom, J. Rizaev, D. Polatova et al.· Cancer Treatment and Researc...· 0 citations
Examination of molecular circuitry linking pyroptosis with inflammasomes, metabolic stress, mitochondrial dysfunction, hypoxia, and epigenetic regulation in HCC suggests regulated pyroptosis may represent a promising immunomodulatory framework for improving precision therapy in HCC.
T. Alramadneh, Inoyatillo Kholmurodov, Naina Boboyeva et al.· Clinical Immunology· 0 citations
Gen silencing studies demonstrate that AEG-1 knockdown reduces proliferation, promotes apoptosis, and enhances sensitivity to chemotherapeutic agents such as cisplatin, doxorubicin, and temozolomide, and support its potential as a target for combinatorial therapeutic strategies to improve outcomes in aggressive brain a...
S. Mohammad, A. Vasudevan, M. Al-Khreisat et al.· Tissue & Cell· 0 citations
This review aims to examine the emerging roles of OSM in BC, elucidate its multifunctional role in tumor regulation and progression, and ultimately explore therapeutic strategies developed to modulate this cytokine in the context of BC.
Muslem Nuseir, Farrukh Ismatov, A. Abdulqader et al.· IUBMB Life - A Journal of th...· 0 citations
A comprehensive analysis of ML-driven methodologies for denoising, spectral decomposition, feature extraction, and high-accuracy classification in CQD fluorescence systems shows how ML enables ultra-low-level analyte detection, interpretable photophysical modeling, and real-time intelligent sensing across chemical and...
B. T. Sayed, Maharshi B. Shukla, Sumit Sharma et al.· RSC Advances· 0 citations
This review argues that circular topology should be viewed as an active pharmacologic variable, not merely a stability enhancement, and dissect recent advances in cap-independent translation initiation, including IRES elements and m6A-driven mechanisms, rolling-circle translation for multi-epitope vaccine design, and p...
Amr A. El-Sehrawy, H. Al-Ameer, J. Rizaev et al.· Biotechnology and Bioenginee...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
