Dong-Gun An

How sparse can a fly-brain model be? Connection strength, wiring placement, network state and task jointly determine function-preserving compression of the Drosophila connectome

Whole-brain connectomes are increasingly used as wiring diagrams for spiking simulations and as structural priors for artificial networks, usually after an ad hoc synapse-count threshold whose effect on validated function has never been measured. We define function-preserving sparsification—removing edges under a fixed...