Author

Dong Gyu Lee

2 papers indexed here

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Open access Oct 2026

Baloxavir-Based Combination Therapy for Protection against Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Mice

Highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus continues to cause animal outbreaks and sporadic zoonotic infections. In a mouse model of lethal influenza disease, we compared oseltamivir, baloxavir, and molnupiravir monotherapies with 2-drug combinations. Baloxavir-based combinations improved survival,...

S. Min, Ju Ryeong Lee, Beom Kyu Kim et al. · Emerging Infectious Diseases · 0 citations

Open access Jul 2026

Capless self-amplifying mRNA vaccine induces dose-sparing protective immunity against HPAI clade 2.3.4.4 H5 virus in mice.

Findings support CLsamRNA as a distinct cap-independent RNA vaccine platform with dose-sparing protective efficacy against HPAI H5 viruses and supportatic optimization of key genetic elements enhanced antigen expression from the CLsamRNA backbone.

Beom Kyu Kim, Ji-Hyun Park, Won-Suk Choi et al. · Molecular Therapy · 1 citation