Sep 2026
Differential aggregation and seeding of tau microtubule-binding region fragments in vitro.
A dissociation between sequence determinants of mature fibril formation and cellular tau seeding is demonstrated and exposure of R2 is identified as a potential feature of propagation-competent tau.
Min-Seok Kim, Seong-Jun Hwang, Dong-Hou Kim et al.
· Biochemical and Biophysical... · 0 citations