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Dong-Hua Chen

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Open access Sep 2026

Structural basis of a SWI/SNF-associated transcription pre-initiation complex.

The mating type switching/sucrose non-fermenting (SWI/SNF) chromatin remodeling complex removes and repositions nucleosomes at promoters for the initiation of transcription. Though long thought to function independently, we find that SWI/SNF is an integral component of the transcription machinery. SWI/SNF associates wi...

S. Nagai, Chun Yang, Dong-Hua Chen et al. · 1 citation

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