Open access
Sep 2026
Construction and evaluation of an independently generated transgenic mouse model carrying mutated human HRAS genes for short-term carcinogenicity assessment
The study aimed to construct and evaluate an independently generated transgenic mouse model applied to the short-term carcinogenicity assessment. Mutated human HRAS fragment containing an intron point-mutation was inserted into C57BL/6JGpt mice via bacterial artificial chromosome transgenic technology, eventually gener...
Wen-You Zeng, Yan-Lin Zhang, Xiaoliu Yang et al.
· Transgenic research · 0 citations