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Dong-Tai Shen

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Open access Oct 2026

Macrophage-derived FKBP5 exacerbates myocardial injury post-infarction in chronic kidney disease via the HSP90/HIF-1α signaling pathway

Chronic kidney disease (CKD) is a frequent and lethal comorbidity in patients with acute myocardial infarction (AMI). This study aimed to quantify the clinical impact of CKD on post-MI outcomes and investigate the molecular mechanisms of cardiorenal crosstalk involving FKBP5. We analyzed MI populations fro...

W. Zhang, X. Gao, J.-M. Chen et al. · 0 citations

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