Open access
Aug 2026
Circulating Cell-Free Mitochondrial DNA as a Redox-Associated Marker of Mitochondrial Homeostasis Disruption during Gastric Carcinogenesis.
A redox-associated model of mitochondrial homeostasis that links impaired mitochondrial maintenance, mtDNA instability, and ccf-mtDNA accumulation is supported to provide a tissue-anchored mechanistic basis for the circulating mtDNA changes detected by plasma-based approaches in GC.
Tie Zhao, Justice Afrifa, Ying-Wei Xue et al.
· Free Radical Biology & Medic... · 0 citations