Drashti Thanki

Synthesis and Computational Evaluation of Substituted Analogues of 4-Sulfonamide Phenylhydrazones as Potential Anticancer Agents: Molecular Docking, Physicochemical Properties, ADME-Tox, and DFT Analysis.

INTRODUCTION Ten derivatives of benzenesulfonamide (SBB-1 to 10) have been synthesized via the condensation of terminal ketone and aldehyde with aromatic 4-sulfonamide phenylhydrazine. METHODS 1H NMR, 13C NMR, IR, UV, and GC-MS were used to confirm the synthesized derivatives. The in vitro cytotoxicity of the synthes...