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Duc-Tai Nguyen

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#machine learning Preprint Sep 2026

Is H&E Image-to-Spatial Transcriptomics Simpler Than It Looks?

Decomposing MSE into slide-level and within-slide components, it is found that the within-slide component has lower residual-normalized parameter sensitivity in controlled neural experiments, which motivates Component-Guided Loss (CGL), which increases supervision of the within-slide component.

Duc-Tai Nguyen, Thanh Ha Do, Phuong-Thao Cao et al. · 0 citations

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