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Author

Dustin E. Bosch

2 papers indexed here

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Open access Aug 2026

Targeting Circulating Fatty Acid Binding Protein 4 Ameliorates Obesity-Associated Hepatic Steatosis.

BACKGROUND & AIMS Obesity is a major driver of metabolic dysfunction-associated steatotic liver disease (MASLD), yet the molecular mechanisms linking excess adiposity to hepatocellular lipid accumulation remain incompletely defined. We investigated whether circulating fatty acid-binding protein 4 (FABP4) mediates adipo...

Xingshan Jiang, Anthony Avellino, Jianyu Yu et al. · 0 citations
Open access Aug 2026

Secreted nuclease effector neutralization by active site mimicry in Bacillota

ABSTRACT Polymorphic toxins mediate interbacterial antagonism among competitors in the gut microbiome. Nuclease effectors, distantly related to the type VI-secreted Bacteroidales Tde, are enriched in human gut Bacillota. Tde mediates antagonism among Bacillota, and expression of the cognate immunity, Tdi, in recipients...

Romina Abbasian, Bishal Parajuli, Liping Yu et al. · 0 citations

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