Safety of Bivalirudin Use in Critically Ill Children: A Single-Center Experience.
OBJECTIVES Bivalirudin, an IV direct thrombin inhibitor, is increasingly used as an alternative anticoagulant in pediatric patients on mechanical circulatory support, with heparin failure, or for heparin-induced thrombocytopenia. Data on its use for treatment or prevention of venous or arterial thromboses in children a...