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E. Acar

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Open access Oct 2026

Synthesis, Characterization, and Anticancer Activity of Pyrene‐Based Schiff Base Ligands and Their Transition Metal Complexes

This study details the synthesis, characterization of unsymmetrical Schiff base ligand and their metal complexes Ni(II), Zn(II), Pb(II), and Cu(II) for anticancer assessment. These ligands were prepared by condensation reaction between 1,2‐phenylenediamine in combinations with 2,5‐dihydroxybenzaldehyde, 1‐pyrenecar...

Hilal Ay, O. Sahin, S. Karakurt et al. · 0 citations
Sep 2026

Suppressing Liver Cancer via the VEGFR1 Receptor using De novo Ellagic Acid Derivatives and Co-drugs: Comprehensive In silico Biochemistry Research with ADMET, RMSD, Molecular Docking, and Molecular Dynamics Simulations.

F fluorinated Ellagic acid derivatives could be considered as potential inhibitors of VEGFR1 due to their favorable binding characteristics and structural stability, along with predicted good ADMET properties without QikProp toxicity alerts.

Soykan Ağar, E. Acar, Ozan Aldemir et al. · 0 citations

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