Induced pluripotent stem cells (iPSCs) provide a scalable platform for off-the-shelf immune cell therapies; however, the mechanisms controlling maturation and functional specialization of iPSC-derived natural killer (iNK) cells are not fully understood. In this study, we combined single-cell transcriptomics, phenotyp...
C. Marsal, Muhammad Kashif, Sophia Borate et al.· Frontiers in Pharmacology· 0 citations
A clinically approved PDGFRβ-targeted PET-imaging platform for longitudinal assessment of fibrotic activity in STEMI patients and preliminary observations suggest that myofibroblast activation persists for up to 2 months after STEMI in selected patients establish a translational therapeutic-diagnostic framework for ind...
Karl-Henrik Grinnemo, Ken Braesch-Andersen, Johan O. Wedin et al.· Cell Stem Cell· 1 citation
It is demonstrated that primary human NK cells are infected by HSV1716 and undergo functional and phenotypic changes, leading to a diminished cytotoxic capacity.
K. Susek, D. Holla, C. Marsal et al.· Frontiers in Immunology· 0 citations
Addressing challenges facing the clinical translation of NK cell therapies was one of the issues discussed in the NK & ILC Symposium that took place in Freiburg, Germany from March 11 to 13, 2026, as the annual meeting of the NK & ILC study group of the German Society for Immunology.
L. Knapp, Katharina Sophie Fischer, Janika Sosat et al.· Human Gene Therapy· 0 citations
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