Open access
Aug 2026
Inhibition of HOX/PBX Dimers as a Potential Therapeutic Strategy in Breast Cancer Subtypes Including Triple Negative Breast Cancer
It is demonstrated that reversing epigenetic changes in TNBC-derived cell lines significantly alters HOX expression and generally reduces sensitivity to HTL-001, and HTL-001 shows synergistic interactions with several established chemotherapeutic agents in vitro.
Richard Morgan, Guy Simpson, E. Arunachalam et al.
· Current Issues in Molecular... · 0 citations