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E. Arunachalam

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Open access Aug 2026

Inhibition of HOX/PBX Dimers as a Potential Therapeutic Strategy in Breast Cancer Subtypes Including Triple Negative Breast Cancer

It is demonstrated that reversing epigenetic changes in TNBC-derived cell lines significantly alters HOX expression and generally reduces sensitivity to HTL-001, and HTL-001 shows synergistic interactions with several established chemotherapeutic agents in vitro.

Richard Morgan, Guy Simpson, E. Arunachalam et al. · 0 citations

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