Ass associations of PA, systolic (SBP) and diastolic (DBP) blood pressure spanning 14 years, with end-of-study cognitive performance in 3,093 participants in the All of Us Research Program (AoU), underscore the potential role of PA promotion and optimal blood pressure management in supporting cognitive health.
O. Okusaga, Yi-Sian Lin, E. Atkinson· Scientific Reports· 0 citations
Admixed individuals have been understudied in medical research largely due to their complex genetic ancestries. However, the consideration of admixture can identify ancestry-enriched genetic associations, delineating genetic underpinnings of cross-population phenotypic variation. Here, we performed admixture mapping in...
R. Mandla, Zhuo-Zheng Shi, Kangcheng Hou et al.· Nature Communications· 0 citations
Biobanks increasingly include individuals with admixed genomes, yet conventional genome-wide association study frameworks either exclude participants who cannot be confidently assigned to a discrete ancestry group or ignore ancestry-specific effects. We present FELIX, a scalable framework for local-ancestry-aware genet...
L. Hu, T. Tan, K. Yuan et al.· medRxiv· 0 citations
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