E. Ay-Albrecht

A new high-accuracy QSAR model based on ultra-curated data for predicting thyroid receptor-related endocrine activity

Introduction Endocrine active substances interfere with hormone signalling and represent a major regulatory concern. The thyroid system is particularly vulnerable, with disruption linked to neurodevelopmental, metabolic, and cardiovascular effects. Current in vitro assays may improve mechanistic understanding but are r...