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Author

E. Benarroch

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Review Oct 2026

What Is the Role of the Locus Coeruleus in Sleep, Cerebrovascular Control, and Glymphatic Clearance?

The locus coeruleus (LC) has a major role in mechanisms of arousal, attention, and emotional responses. Increasing evidence indicates that the LC also regulates sleep architecture and triggers phasic autonomic and hemodynamic events during non-rapid eye movement (NREM) sleep. Ultraslow oscillations of LC activity reduc...

Pablo R. Castillo, E. Benarroch · 0 citations

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