Open access
Sep 2026
Locus Coeruleus mediates the pharmacological effects of 2-Pentadecyl-2-oxazoline in a mouse model of neuropathic pain.
A chemogenetic approach is employed to chronically silence LC noradrenergic neurons in a male mouse model of neuropathic pain induced by spared nerve injury and results suggest a therapeutic relevance of C15OXA in neuropathic pain and support a possible involvement of the LC in mediating its behavioral and molecular ef...
F. Ricciardi, M. Llorca-Torralba, L. Luongo et al.
· Neuropharmacology · 0 citations