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Author

E. Bertosin

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Open access Oct 2026

A modular DNA toolkit for single-molecule biophysics

Long, customizable DNA molecules are an essential tool for in vitro single-molecule biophysics. Most studies still rely on the λ-phage genome, which has a fixed sequence, a non-uniform GC distribution, and limited options for modification. To overcome these limitations, we developed a modular DNA (ModDNA) toolkit that...

J. van der Torre, R. Barth, Klaudia Majszczyk et al. · 1 citation
Open access Sep 2026

Dilatable DNA origami nanopores as nuclear pore mimics

The nuclear pore complex (NPC) is a massive protein system that controls all nucleocytoplasmic transport via a dynamic network of intrinsically disordered proteins called FG-Nups. We developed an NPC-mimicking DNA origami nanostructure that self-assembles into a tetrameric, octagonal nanopore with an inner diameter tha...

E. Bertosin, B. Van Herck, Anders Barth et al. · 0 citations

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