Abatacept in combination with ATLG reduces acute GvHD incidence and improves outcomes of children transplanted from mismatched unrelated donors: a real-world, multicenter, retrospective study.
BACKGROUND The use of HLA-mismatched donors has been associated with increased risk of both acute and chronic Graft versus Host Disease (GvHD). The use of abatacept (ABA) reduces the risk of acute GvHD. ABA data in pediatric patients and in combination with serotherapy are limited. OBJECTIVE We hypothesized that addi...