Evelyn Chang

Dendrimer 'protein corona': mechanism of interaction, characterization, and implications in drug delivery.

Upon exposure to biological fluids, nanoparticles immediately interact with endogenous proteins and biomolecules, acquiring a 'protein corona' that significantly influences their in vivo behavior. Dendrimers are ultrasmall, highly branched nanocarriers whose physicochemical properties and cargo conjugation can be preci...