As a result of investigation of glycosidic composition of the sea cucumber Ocnus glacialis (Cucumariidae, Dendrochirotida) two new glycosides, glacialisosides A (1) and B (2), were isolated. Their structures were established by in-depth analysis of 1H, 13C NMR, 1D TOCSY, and 2D NMR (1H,1H COSY, HMBC, HSQC, ROESY), in a...
A. Silchenko, E. Chingizova, E. Menchinskaya et al.· Marine Drugs· 0 citations
Current Parkinson’s disease (PD) therapies like Levodopa (L-DOPA) only provide symptomatic relief, highlighting the need for multi-target neuroprotective agents. This study investigates the mechanisms and preclinical effects of trans-vitisin B (tVB), an oligomeric stilbene, in PD models. In LPS-stimulated HMC3 and RAW...
Evgeniy A. Pislyagin, I. Manzhulo, Irina Agafonova et al.· Antioxidants· 0 citations
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