403. Sustained administration of the full and partial agonists of trace amine associated receptor 1 (TAAR1) induces different effects on the excitability of central monoaminergic neurons
Abstract Background Trace amine associated receptor 1 (TAAR1) is a promising target for the next generation of the central nervous system (CNS) drugs. It has been previously shown that the full (RO5256390) and partial (RO5263397) agonists of TAAR1 had anti-addictive, pro-cognitive, and antipsychotic- and antidepressant...