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E. Elkordy

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Open access Jul 2026

Vitamin a modulates neurogenesis-associated pathways and cholinergic signaling in Alzheimer’s disease: potential role of reactive astrocytes via NGN2/SOX-11 and SIRT-1

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder lacking effective disease-modifying therapies. A promising regenerative approach involves enhancing endogenous neurogenic capacity within the injured brain. Reactive astrocytes—stellate-like cells in the AD brain—may contribute to a pro-neurogenic env...

N. S. El-Mezayen, Yara Alaa Eesa, Wed Alaa Hassan et al. · 0 citations

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