As germline genetic testing indications expand, barriers to testing persist. We evaluated the feasibility of a novel approach in which patients with cancer underwent genetic testing first, with follow-up genetic counseling only for those found to have a germline pathogenic variant (PV).
Patients with advan...
Kara K. Landry, W. Mckinnon, Heather M. Feldman et al.· Hereditary Cancer in Clinica...· 0 citations
Paired GGT and CGP testing had high rates of clinically significant findings with the most frequent being high tumor mutation burden status, and pathway and mutational signature analysis revealed frequent CGP mutations in DNA repair and cell cycle pathways.
P. L. Serrano Usón, Jacquelyn Reuther, M. Golafshar et al.· Gastro Hep Advances· 0 citations
Utilization of risk-reducing surgery was highest in women with BRCA1/2 PV, and Pancreatic screening was low in all patients, and future studies are needed to examine the factors underlying these trends.
Emily M. Russell, S. Nielsen, R. Ellsworth et al.· JCO Precision Oncology· 0 citations
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