Open access
Aug 2026
Vacuolar type H+ ATPase is involved in stress responses in Leishmania mexicana by regulating the lysosomal pH
Data support a canonical function for the Leishmania v-ATPase in lysosome acidification and autophagy, which is essential for parasite differentiation, and identify the poorly characterized Leishmania CVC as another major site of v-ATPase concentration.
Ç. Alagöz, Andreia Albuquerque-Wendt, E. Gluenz
· bioRxiv · 0 citations