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E. Godzhello

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Open access Sep 2026

Systemic–local immune remodeling in colorectal cancer: CD14+ cell-derived cytokine responsiveness, mucosal immune-cell organization, and exploratory metastasis-associated patterns

Background Immune regulatory networks contribute to colorectal cancer (CRC) progression, but most clinical studies focus on tissue immune-cell abundance or static inflammatory mediators. We investigated cytokine-response patterns in cultures derived from peripheral-blood CD14+ cells and local immune-cell composition in...

N. Shakhpazyan, L. Mikhaleva, N. Sadykhov et al. · 0 citations

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