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E. Hancock

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Open access Jul 2026

VirD4 coupling proteins suppress accumulation of conjugative pili produced by type IV secretion systems

It is proposed that the binding of a cognate DNA substrate triggers the T4CP to suppress pilus production by blocking elongation, or stimulating retraction or release, which transitions the T4SS from its default pilus-generating (mate-seeking) mode to the activated DNA-translocation (mating) machine.

Pratick Khara, E. Hancock, Kouhei Kishida et al. · 0 citations

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