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E. Holland

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Open access Sep 2026

FFPE-CUTAC: A Single Assay, Multiple Layers

Background Archival biobanks of formalin-fixed paraffin-embedded (FFPE) specimens represent a vast and underused resource for retrospective molecular studies linked to clinical follow-up. However, fixation-induced chemical modification and nucleic acid fragmentation limit scalable genomic and transcriptomic profiling....

Yi Niu, Qun-Zhi Xu, Chun-Yin Mak et al. · 0 citations
Open access Aug 2026

Loss of MSH6 or MSH2 sensitizes progressive glioblastoma to radiotherapy

<strong>A prime resistance mechanism of glioblastoma to temozolomide is a vulnerability to radiation therapy</strong>

Vlad Moisoiu, Roxanne Lourman, Frank Szulzewsky et al. · 0 citations

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