Review
Open access
Aug 2026
Citrullination and Deamidation in Type 1 Diabetes: Linking Beta Cell Stress to Neoantigen‐Driven Autoimmunity
Citrullination and deamidation are post‐translational modifications (PTMs) increasingly recognized as important contributors to neoepitope formation in type 1 diabetes (T1D). Under inflammatory and endoplasmic reticulum stress conditions, beta cells activate calcium‐dependent peptidylarginine deiminase and transglutami...
A. Callebaut, Ylke Bruggeman, C. Mathieu et al.
· Immunological Reviews · 0 citations