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Review Jun 2026

Cycloaddition Reactions as a Tool for Expanding Chemical Space of DNA-Encoded Libraries

DNA-encoded libraries (DELs) have emerged as a powerful platform for high-throughput hit identification in drug discovery, yet the repertoire of DNA-compatible reactions for library construction remains limited. Cycloaddition reactions offer a particularly attractive solution, enabling the simultaneous construction of...

Jihyun Kim, E. Jang, Jaehoon Sim · 0 citations

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