Author

E. Lacivita

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Open access Sep 2026

Treatment with Ureidopropanamide Formyl Peptide Receptor 2 Agonists Attenuates Brain Changes Induced by Systemic Lipopolysaccharide Administration in Rats

Multiple lines of evidence highlight the impact of the resolution of inflammation (RoI) on mitigating the inflammatory response and restoring homeostasis in the brain. Recently, the significance of formyl peptide receptor 2 (FPR2) in this process has been emphasized due to its remarkable ability to interact with a wide...

K. Tylek, K. Kamińska, E. Trojan et al. · ACS Omega · 0 citations

Open access Jun 2026

Toward a Therapy for Autism Spectrum Disorder: The Formyl Peptide Receptor 2 Agonist MR-39 Supports Synaptic Health in the BTBR Mouse and Features a Favorable Safety Profile.

This study confirmed that promoting inflammation resolution with MR-39 can open new therapeutic options for ASD and that this compound has potential as a drug.

Daniele Vitone, Fabio Francavilla, M. Ferraro et al. · ACS Pharmacology & Translati... · 0 citations