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Open access Nov 2026

Validation of senescence as a therapeutic target in metabolic dysfunction-associated steatohepatitis (MASH) through navitoclax delivery.

Metabolic dysfunction-associated steatohepatitis (MASH) is a chronic liver disease characterized by steatosis, inflammation, and progressive fibrosis. Increasing evidence suggests that cellular senescence contributes to MASH progression by promoting lipid accumulation, inflammatory signaling, and fibrogenic responses,...

Yi-Di Jiang, Shuang-Mei Li, E. Liehn et al. · 0 citations

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