E. Lysikova

Sex-specific consequences of loss-of-imprinting of the maternally expressed gene Pleckstrin Homology-Like Domain Family A Member 2 (Phlda2) on placental development and fetal growth

Imprinted genes are expressed from one parental allele as a result of epigenetic events initiated in the male and female germlines. We previously identified a role for imprinted genes as master regulators of placental endocrine lineage development in mice. We further reported that loss-of-function of the patern...