E. Milosevic

Association of CSF2, IL12B, IL23R, TNF, IL6 and IL10 Gene Polymorphisms with Susceptibility to Takayasu Arteritis

Background: Takayasu arteritis (TA) is a large-vessel vasculitis with an incompletely understood pathogenesis, in which genetic factors are thought to play an important role. Cytokine-mediated immune pathways, particularly those involving Th1 and Th17 responses, have been implicated in the immunopathogenesis of TA, mak...