Author

E. Oğuz

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Open access Oct 2026

Synthesis, Biological Evaluation, and Molecular Dynamics Studies of Novel 1,2,4-Triazole-Functionalized Benzene-Sulfonate Derivatives as Potential Enzyme Inhibitors and Cytotoxicity in HepG2 Cells

Background/Objectives: In this study, novel benzenesulfonate derivatives containing a 1,2,4-triazole ring were synthesized. Methods: Their molecular structures were characterized by IR, 1H NMR, and 13C NMR spectroscopy, together with Q-TOF LC/MS analyses. For compounds 5b and 5d, the available mass spectrometric data w...

Y. Ünver, F. Türkan, H. Güler et al. · Pharmaceuticals · 0 citations

Sep 2026

A synthetic Benzothiazole-Thiourea Derivative with Multi-Target Potential Activity for Alzheimer's Disease: Antioxidant Properties and Mechanistic Insights.

The antioxidant activity and the potential effects of H74 on multiple targets associated with Alzheimer's disease (AD) were investigated and molecular docking results suggested that H74 might act as a potential inhibitor to these enzymes.

A. Lahouel, Kamel Harrouche, E. Oğuz et al. · Neuropharmacology · 0 citations