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Open access Oct 2026

Age-specific patterns in colorectal cancer incidence and survival over time: a 17-year population-based cancer registry study from northeastern Italy.

BACKGROUND Age-specific differences in colorectal cancer remain insufficiently characterized in studies integrating incidence and survival dynamics. AIMS We analyzed age-specific patterns of colorectal cancer incidence and survival over time using population-based registry data from northeastern Italy, including 16,7...

M. Taborelli, F. Toffolutti, T. Angelin et al. · 0 citations
Open access Sep 2026

Circulating tumor DNA tumor fraction as a biomarker in refractory metastatic colorectal cancer: findings from the CAVE-2 GOIM trial

Liquid biopsy guided anti-EGFR rechallenge therapy is gaining ground as a potential option for patient with refractory metastatic colorectal cancer. However, the identification of potential biomarkers to implement patient's stratification is required. The CAVE-2 GOIM trial investigated the role of rechallenge with cetu...

Davide Ciardiello, G. Martini, Luca Boscolo Bielo et al. · 0 citations

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