Clustered regularly interspaced short palindromic repeats (CRISPR) nucleases with collateral, sequence-activated nuclease activity have been proposed as a route to molecular-grade sensitivity at the point of care, and the proposal is unusually consequential for neglected tropical parasitic diseases, where control and e...
Chidi L. C. Ndukwu, E. Onosakponome· South Asian Journal of Resea...· 0 citations
Emerging and zoonotic parasitic diseases are sustained by transmission systems that cross human, domestic-animal, wildlife, vector, food and environmental compartments. Molecular methods can reveal parasite identity, genetic diversity and connectivity across those compartments, but technological sensitivity alone does...
E. Onosakponome, Chidi L. C. Ndukwu, Sonrandein Ditimi Bodensibari· South Asian Journal of Resea...· 0 citations
Background: Malaria control depends on the continued efficacy of antimalarial drugs and insecticide-based vector control, both of which are increasingly compromised by the evolving genetic capacity of Plasmodium falciparum and Anopheles mosquitoes to resist these tools. Genomic surveillance offers a faster and more spa...
Esiere RoseMary Kaiso, E. Onosakponome· Asian Journal of Research in...· 0 citations
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