Reconstituting Myosin-I-Mediated Branched Actin Assembly in a Bead-Based Actin Comet-Tail Motility Assay.
Branched actin polymerization mediated by the actin-related protein 2/3 (Arp2/3) complex provides the primary pushing forces for a variety of cellular processes, including cell migration, endocytosis, and phagocytosis. Myosin-I motors, which frequently colocalize with branched actin networks at the cell leading edge, h...