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Author

E. Rabiner

2 papers indexed here

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Open access Sep 2026

530. Detecting neuroplastic effects induced by ketamine and classic psychedelics in healthy human subjects

Abstract Background Clinical studies have shown that ketamine and classic psychedelics can produce robust and rapid antidepressant effects after a single or a few administrations. However, the neurobiological mechanisms driving these long-lasting changes remain unclear. A leading framework proposes that both drug class...

C. Agnorelli, J. Peill, D. Kurtin et al. · 0 citations
Aug 2026

In Vivo Rodent Studies with the Novel PET Tracer [18F]PGM028299: An Inhibitor of D-Amino Acid Oxidase.

Abnormal N-methyl-d-aspartate receptor (NMDAr) function is implicated in schizophrenia and other neuropsychiatric disorders. Enhancing NMDAr signaling can be achieved by increasing synaptic d-serine levels through the inhibition of D-amino acid oxidase (DAAO). We report the synthesis and preclinical evaluation of [18F]...

M. Onega, Eimear Howley, Charlotte Fieldhouse et al. · 0 citations

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