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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

E. Rui

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Sep 2026

Abstract B046: Pseudo-irreversible, pan-KRAS inhibitor BH-501284 achieves prolonged inhibition of KRAS signaling leading to deep and durable antitumor efficacy in mouse tumor models

KRAS is a frequently mutated oncogene in pancreatic cancer. Trial success with Switch-II covalent KRAS G12C inhibitors and panRAS tricomplex inhibitors validates KRAS mutations as targetable oncogenic drivers. Yet the development of non-covalent KRAS inhibitors has remained challenging due to the shallow Switch-I...

W. Deng, Nancy Ling, Zhen-Ping Wang et al. · 0 citations

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