Author

E. Schönbrunn

2 papers indexed here

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Open access Aug 2026

Unc-51 like kinase 3 (ULK3) contributes to autophagy and cell survival in multiple myeloma

It is found that ULK3 contributes to autophagy and supports MM cell survival and calls for future development of more selective ULK3-directed therapies, calling for future development of more selective ULK3-directed therapies.

Marilena Tauro, Tao Li, P. Sudalagunta et al. · Nature Communications · 0 citations

Jul 2026

Abstract A053: Discovery and modular design of CDK12–DDB1 molecular glues for targeted Cyclin K degradation

Advanced lead molecules across these series achieve a rare combination of high CDK12/13 selectivity, potent and durable cyclin K degradation, and favorable physicochemical, in vitro ADME, and in vivo PK properties, supporting progression toward IND-enabling preclinical safety evaluation.

Thiyagamurthy Pandurangan, Anna Iermolaieva, Pompom Ghosh et al. · Clinical Cancer Research · 0 citations