Author

E. Shagimardanova

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Open access Sep 2026

Comparative Single-Nucleus Transcriptomic Analysis of the Intact Left Ventricle in Acomys cahirinus and Mus musculus

Background/Objectives: Acomys cahirinus exhibits more favorable cardiac remodeling after ischemic injury than Mus musculus, yet the molecular organization of the intact myocardium remains poorly characterized. This study aimed to identify baseline interspecies differences in the adult left ventricle, with particular em...

Nikita Filatov, Kirill Kokorichev, D. Tychinin et al. · Genes · 0 citations

Open access Oct 2026

Multi-omics analysis reveals tissue-specific patterns of chicken growth driven by metabolic reorganization

Genetic variation in growth rate is associated with substantial metabolic differences in poultry, but its tissue-specific effects remain insufficiently characterized. Using an F2 population derived from Russian Snow White and White Cornish chickens, we profiled liver, leg muscle, and breast muscle from fast-growing (...

V. Kaplan, M. Kulyashov, I. Yevshin et al. · Scientific Reports · 0 citations

Open access Sep 2026

Transcriptional and histopathological profiling of skeletal muscle in Bla/J mice at the stage of dysferlinopathy manifestation.

It is demonstrated that early muscle atrophy and myofiber necrosis in dysferlinopathy occur independently of canonical ubiquitin-proteasome and apoptotic pathways, and the disease manifestation stage is structurally characterized by stalled mitochondrial clearance and a delayed regenerative response.

I. Limaev, N. Gladyshev, I. Yakovlev et al. · Biology Open · 1 citation

Open access Sep 2026

Atlas of cell types and regulatory elements underlying human facial diversity.

Human genetic diversity generates an astonishing variety of facial shapes, and craniofacial anomalies rank among the most common birth defects. Identifying the cellular mechanisms that mediate the genome's influence on facial variation remains a challenge. Here we created a multimodal facial atlas across embryonic week...

A. Erickson, Yaakov Gershtein, Rozalina Galimullina et al. · Nature Genetics · 0 citations

Open access Sep 2026

Genomic spectrum of congenital heart disease combined with kidney and urinary tract anomalies uncovered by exome sequencing and array-CGH

ROBO1 can be regarded as a candidate gene associated with combined heart and kidney structural defects and should be included in appropriate diagnostic gene-sequencing panels and support the usefulness of WES and array-based comparative genomic hybridization (array-CGH) analysis for new candidate gene identification, m...

A. Zlotina, Sergei Zhuk, I. Kozyrev et al. · Frontiers in Cell and Develo... · 0 citations