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Review Open access Oct 2026

Neuronal-surface antibodies are uncommon in patients with a final diagnosis of sporadic Creutzfeldt-Jakob disease: a systematic review and meta-analysis

Neuronal antibodies detected during evaluation of rapidly progressive dementia may indicate treatable autoimmune encephalitis or incidental seroreactivity in prion disease. We estimated their frequency in sporadic Creutzfeldt-Jakob disease (sCJD), separately from diagnostic yield in suspected CJD. Under a re...

N. Qadi, A. Aldakheel, E. Shosha · 0 citations
Review Open access Sep 2026

Pediatric-Onset Multiple Sclerosis in the Gulf: A Scoping Review of the Current Evidence Base and Research Gaps

Background: MS begins before age 18 in 3–10% of cases (pediatric-onset MS, POMS). Adult MS epidemiology is increasingly characterized across the Gulf, but whether the pediatric literature is sufficiently mature and ho0m1ogeneous to support a quantitative meta-analysis, as opposed to a scoping review, remains unclear. O...

E. Shosha, N. Qadi, Rakan S. Alromayan et al. · 0 citations
Review Open access Sep 2026

Recognizing and Differentiating Area Postrema Syndrome Across NMOSD, MOGAD, and GFAP Astrocytopathy

Area postrema syndrome (APS)—intractable nausea, vomiting, and/or hiccups persisting ≤48 h—is a recognized presenting feature of neuromyelitis optica spectrum disorder (NMOSD) and, less commonly, of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and glial fibrillary acidic protein (GFAP)-astroc...

E. Shosha, Jihan Madani · 0 citations

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