Author

E. Skorb

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Open access Sep 2026

Hesperidin reduces genomic instability in glioblastoma cells and is associated with reduced HNRNPA2B1/m6A levels

Genomic instability contributes to tumor progression and limits the effectiveness of anticancer therapy. In this study, we investigated whether the citrus flavonoid hesperidin influences cytogenetic damage and epitranscriptomic markers in tumor cells exposed to ionizing radiation or maintained under long-term culture c...

V. Sazonova, Pavel Zun, Ilia Tonkji et al. · Frontiers in Pharmacology · 0 citations

Review Open access Sep 2026

Bacterial Defense and Phage Counterdefense: Unraveling the Molecular Basis of Phage Resistance

Phage therapy represents a promising strategy against multidrug-resistant bacteria, but its clinical effectiveness is increasingly compromised by the emergence of phage-resistant traits (PRTs). This resistance develops through multiple interconnected mechanisms that operate at different levels of bacterial defense. A...

Kunal Dutta, Kira M. Velieva, E. Skorb et al. · ACS Omega · 0 citations

Open access Aug 2026

Siteomix: a PyMOL plugin for the detection, alignment, and similarity analysis of protein‒ligand binding sites

Siteomix is an integrated plugin for the PyMOL molecular graphics system that automates the detection of binding pockets via the LIGSITE algorithm, visualizes them as discrete point clouds colored by cavity depth, and performs a two-step alignment combining the rigid iterative closest point (ICP) algorithm with differe...

Kira M. Velieva, E. Skorb, S. Shityakov · Journal of Computer-Aided Mo... · 0 citations