Genetic analyses prioritized angiotensin-converting enzyme as a candidate target, and a conventional observational analysis in a large prospective cohort provided supportive evidence that regular angiotensin-converting enzyme inhibitor use was associated with a higher AD risk.
Pei-Guan Huang, Hai-Bo Tang, Ze-Ying Feng et al.· Journal of the American Hear...· 0 citations
Autistic individuals may be at an increased risk of hazardous drinking compared to non-autistic counterparts: potential motivations include facilitated social interactions and self-medication of co-occurring difficulties, and possible risk factors include being older and female. However, research remains limited and ce...
S. Page, K. Easey, F. Sedgewick et al.· medRxiv· 0 citations
Findings may be due to methodological shortcomings, including weak instruments biasing effects towards to the null, but it is plausible that genetic liability for autism does not directly increase the amount of alcohol consumed but instead operates via commonly co-occurring difficulties in the autistic community.
S. Page, K. Easey, F. Sedgewick et al.· medRxiv· 0 citations
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